[The influence of ethrane on the electro- and pentylenetetrazol-convulsions in mice (author's transl)].

The influence of Ethrane upon electro shock and pentylenetetrazol-induced convulsions was studied in mice. Similar to other inhalation anaesthetics and to barbiturates Ethrane exerts a powerful anticonvulsive activity. There is a dose response relationship between the rate of electro shock (20 mA/0.2 sec) induced convulsions and inspiratory Ethrane concentration, convulsions being completely prevented by 1.5 vol.-percent of Ethrane. The LD(50) of pentylentetrazol increases five fold under a 2 vol.-percent Ethrane anaesthesia.