Polish journal of radiology · 2016
Serum ACE Level in Sarcoidosis Patients with Typical and Atypical HRCT Manifestation.
СтатьяНазвание и аннотация: Перевод в очереди
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Kahkouee Shahram, Samadi Katayoon, Alai Ali, Abedini Atefeh, Rezaiian Lida
Аннотация
BACKGROUND: Sarcoidosis is an inflammatory disease that affects multiple organs. Before widespread use of computed tomography (CT), the severity of sarcoidosis was assessed based on chest X-ray abnormalities. HRCT can distinguish between active inflammatory changes and irreversible fibrosis. In this study, we analyzed different ACE levels in 148 patients diagnosed with sarcoidosis.
MATERIAL/METHODS: We categorized these patients based on their HRCT results into four groups: 1) patients diagnosed with chronic disease; 2) patients diagnosed with non-chronic disease; 3) patients who exhibited typical HRCT changes; and 4) patients who exhibited atypical HRCT changes. Afterward the mean ACE level of each group was calculated and compared.
RESULT: The HRCT scans of chronic sarcoidosis patients tended to show more atypical sarcoidosis patterns. Moreover, there was a reverse correlation between chronicity and ACE level (P-value <0.05).
CONCLUSIONS: HRCT is another modality which would be useful when the diagnosis of sarcoidosis is not definite.
MATERIAL/METHODS: We categorized these patients based on their HRCT results into four groups: 1) patients diagnosed with chronic disease; 2) patients diagnosed with non-chronic disease; 3) patients who exhibited typical HRCT changes; and 4) patients who exhibited atypical HRCT changes. Afterward the mean ACE level of each group was calculated and compared.
RESULT: The HRCT scans of chronic sarcoidosis patients tended to show more atypical sarcoidosis patterns. Moreover, there was a reverse correlation between chronicity and ACE level (P-value <0.05).
CONCLUSIONS: HRCT is another modality which would be useful when the diagnosis of sarcoidosis is not definite.