Deutsche medizinische Wochenschrift (1946) · 2004
[Portal vein thrombosis in a patient with lowered protein S level].
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Fechner L, Lotterer E, Fleig W E
Аннотация
HISTORY AND CLINICAL FINDINGS: In a 39-year-old man with increasing spasmodic epigastric pain, nausea and vomiting, varices of the esophagus and the gastric fundus were found endoscopically.
INVESTIGATIONS: A portal vein thrombosis and a consecutive thrombosis of the splenic vein were diagnosed by colour Doppler sonography and angio CT. A protein S deficiency (59 %) was found to be the underlying illness.
TREATMENT AND COURSE: The thrombosis and the resulting clinical symptoms completely resolved shortly after starting therapeutic heparinization. For six months, the patient has been without complaints or clinical symptoms.
CONCLUSION: Hence, an isolated protein S deficiency can be the cause for a portal vein thrombosis.
INVESTIGATIONS: A portal vein thrombosis and a consecutive thrombosis of the splenic vein were diagnosed by colour Doppler sonography and angio CT. A protein S deficiency (59 %) was found to be the underlying illness.
TREATMENT AND COURSE: The thrombosis and the resulting clinical symptoms completely resolved shortly after starting therapeutic heparinization. For six months, the patient has been without complaints or clinical symptoms.
CONCLUSION: Hence, an isolated protein S deficiency can be the cause for a portal vein thrombosis.