Multi-templates surface molecularly imprinted polymer for simultaneous and rapid determination of sulfonamides and quinolones in water: effect of carbon-carbon double bond.

In this work, the effect of a carrier modified with a carbon-carbon double bond (C=C) on preparing multi-templates surface molecularly imprinted polymer MIP (C=C@MIP) for simultaneous detection of sulfonamides and quinolones was investigated. The results showed that the adsorption capacities of the C=C@MIP were obviously higher than those of MIP, which is the carrier without modified C=C, suggesting that C=C played a key role in preparing MIP with higher adsorption capacities. Then, C=C@MIP was used as adsorbents for solid-phase extraction (SPE) and coupled with high-performance liquid chromatography (HPLC) for the simultaneous determination of sulfonamides and quinolones in water. The method showed excellent applicability, with the adsorption capacities of 19.92, 16.38, 12.92, 18.37, 14.49, 12.01, 16.98, 23.33, and 14.29 mg/g for SDZ, STZ, SMZ, SMX, SDM, ENRO, OFL, LOME, and GATI, respectively. The spiked recoveries and relative standard deviations (RSDs) of sulfonamides and quinolones using C=C@MIP were 81.59-100.7 % and 3.75-7.37 %, respectively. The limits of detection (LODs) for SDZ, STZ, SMZ, SMX, SDM, ENRO, OFL, LOME, and GATI were 0.013, 0.012, 0.012, 0.013, 0.014, 0.012, 0.013, 0.015, and 0.015 μg/L, respectively.