Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye · 2010
Endophthalmitis caused by Stenotrophomonas maltophilia.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Chen Kuan-Jen, Wang Nan-Kai, Sun Ming-Hui, Chen Tun-Lu, Lai Chi-Chun, Wu Wei-Chi, Tan Hsin-Yuan
Аннотация
BACKGROUND AND OBJECTIVE: The authors investigate clinical settings, antibiotic susceptibility and resistance patterns, and visual outcomes associated with endophthalmitis caused by Stenotrophomonas maltophilia.
PATIENTS AND METHODS: Records of six patients with S. maltophilia endophthalmitis between January 1, 1998, and December 31, 2007, were reviewed.
RESULTS: Clinical settings included post-trauma (2 eyes), post-cataract extraction (2 eyes), post-keratoplasty with keratitis (1 eye), and post-vitreous lavage (1 eye). Presenting visual acuity ranged from counting fingers to no light perception. Final visual acuity ranged from 10/20 to no light perception. Initial treatment included pars plana vitrectomy in 4 eyes and tap in 2 eyes. Most isolates were susceptible to fluoroquinolones (ciprofloxacin, levofloxacin, or moxifloxacin) and sulfamethoxazole-trimethoprim; however, they were resistant to ceftazidime and aminoglycosides.
CONCLUSION: S. maltophilia is an uncommon causative agent of endophthalmitis and is resistant to commonly used antibiotics, such as ceftazidime and aminoglycosides. Based on in vitro antibiotic susceptibility testing, sulfamethoxazole-trimethoprim and new-generation fluoroquinolones may be preferable in the treatment of endophthalmitis caused by S. maltophilia.
PATIENTS AND METHODS: Records of six patients with S. maltophilia endophthalmitis between January 1, 1998, and December 31, 2007, were reviewed.
RESULTS: Clinical settings included post-trauma (2 eyes), post-cataract extraction (2 eyes), post-keratoplasty with keratitis (1 eye), and post-vitreous lavage (1 eye). Presenting visual acuity ranged from counting fingers to no light perception. Final visual acuity ranged from 10/20 to no light perception. Initial treatment included pars plana vitrectomy in 4 eyes and tap in 2 eyes. Most isolates were susceptible to fluoroquinolones (ciprofloxacin, levofloxacin, or moxifloxacin) and sulfamethoxazole-trimethoprim; however, they were resistant to ceftazidime and aminoglycosides.
CONCLUSION: S. maltophilia is an uncommon causative agent of endophthalmitis and is resistant to commonly used antibiotics, such as ceftazidime and aminoglycosides. Based on in vitro antibiotic susceptibility testing, sulfamethoxazole-trimethoprim and new-generation fluoroquinolones may be preferable in the treatment of endophthalmitis caused by S. maltophilia.
Предметные рубрики MeSH
AdultAgedChild, PreschoolDrug Resistance, BacterialEndophthalmitisEye Infections, BacterialEye Injuries, PenetratingFemaleFluoroquinolonesGram-Negative Bacterial InfectionsHumansMaleMicrobial Sensitivity TestsPhacoemulsificationStenotrophomonas maltophiliaSurgical Wound InfectionTrimethoprim, Sulfamethoxazole Drug CombinationVisual AcuityWounds, Nonpenetrating