Clinical and experimental hypertension (New York, N.Y. : 1993) · 2012
Improving drug adherence using fixed combinations caused beneficial treatment outcomes and decreased health-care costs in patients with hypertension.
СтатьяМногоцентровое исследованиеНаблюдательное исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Kumagai Naoto, Onishi Katsuya, Hoshino Kozo, Nakamori Shiro, Kitai Tamaki, Yazu Takahiro, Oota Masahiro, Ueda Yuji, Hiraoka Naoto, Okamoto Shinya, Yamada Tomomi, Dohi Kaoru, Nakamura Mashio, Ito Masaaki
Аннотация
We enrolled 196 patients with hypertension who were already being treated with free-drug combinations of angiotensin-II receptor blocker (ARB) and amlodipine. The free-drug combinations of ARB and amlodipine were replaced with the same dose of the fixed-dose combinations. The average home blood pressure (BP) in all patients receiving fixed-dose combinations was significantly lower than those receiving free-drug combinations (131 ± 10/75 ± 8 vs. 136 ± 11/77 ± 9 mm Hg, P < .01) accompanied with increasing drug adherence. After lowering BP by fixed-dose combinations, the costs for medications decreased by 31% over the 3 months.
Предметные рубрики MeSH
AgedAged, 80 and overAmlodipineAngiotensin Receptor AntagonistsBenzimidazolesBenzoatesBiphenyl CompoundsBlood PressureBlood Pressure Monitoring, AmbulatoryCalcium Channel BlockersDose-Response Relationship, DrugDrug Therapy, CombinationFemaleHealth Care CostsHumansHypertensionMaleMedication AdherenceMiddle AgedProspective StudiesRetrospective StudiesTelmisartanTetrazolesTreatment OutcomeValineValsartan