Fortschritte der Medizin · 1996
[Torasemide in patients with chronic heart failure. Results of clinical administration in general practice].
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Wittig T, Medert G
Аннотация
METHOD: A total of 1,650 patients with congestive heart failure where followed up prospectively for 1 to 2 months with the aim of obtaining further information about the therapeutic effects of torasemide under doctor's office conditions.
RESULTS: The efficacy and tolerability of the substance matched those previously established in controlled clinical trials. Torasemide brought about the greatest improvement in cardiac performance in patients with initially severe symptoms and/or which had not received prior diuretic treatment. However, even those who had already received a diuretic, also benefitted greatly from the change over to torasemide. Present results also confirmed the findings of controlled studies with respect to an absence of an effect on potassium levels, blood glucose and uric acid. Torasemide was well tolerated and no previously unknown or severe adverse reactions were observed. Among physicians 95.1%, and among patients 93.6%, assessed their experience with torasemide to be good or excellent.
RESULTS: The efficacy and tolerability of the substance matched those previously established in controlled clinical trials. Torasemide brought about the greatest improvement in cardiac performance in patients with initially severe symptoms and/or which had not received prior diuretic treatment. However, even those who had already received a diuretic, also benefitted greatly from the change over to torasemide. Present results also confirmed the findings of controlled studies with respect to an absence of an effect on potassium levels, blood glucose and uric acid. Torasemide was well tolerated and no previously unknown or severe adverse reactions were observed. Among physicians 95.1%, and among patients 93.6%, assessed their experience with torasemide to be good or excellent.