Journal of science and medicine in sport · 2019
Why exercise may be beneficial in concussion rehabilitation: A cellular perspective.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
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Dech Ryan T, Bishop Scott A, Neary J Patrick
Аннотация
INTRODUCTION: Concussion diagnosis and rehabilitation management has become a prevalent area of research, and yet much is still unknown about these complex injuries. Historically, exercise prescription post-concussion was conservatively used for rehabilitation due to the suspected harmful effects that exercise can have on damaged neurons, and increase in symptoms. However, there has been a shift to implement exercise earlier into recovery as several studies have demonstrated positive outcomes.
OBJECTIVE: The objective of this literature review is to update the reader about new advances in concussion research related to the beneficial effects of physical activity from both a neurometabolic and a broader physiological perspective, using gene expression as a vehicle to demonstrate why and how physical activity has the capacity to optimize recovery from a cellular perspective. To further this clinical guideline, the evidence must continue to support these positive outcomes from an inductive and deductive physiologic approach (i.e., the clinical evidence aligned from a micro- to macroscopic approach and vice versa).
DESIGN: Narrative review.
METHODS: Pubmed and Medline were used with the following key words: concussion and, physical activity, neurometabolic, gene regulation, trauma, nervous system, mild head injury, acute exercise, cellular physiology and pathophysiology.
CONCLUSION: It is our contention that understanding the cellular perspective will help guide clinical management, and promote research into post-concussion exercise.
OBJECTIVE: The objective of this literature review is to update the reader about new advances in concussion research related to the beneficial effects of physical activity from both a neurometabolic and a broader physiological perspective, using gene expression as a vehicle to demonstrate why and how physical activity has the capacity to optimize recovery from a cellular perspective. To further this clinical guideline, the evidence must continue to support these positive outcomes from an inductive and deductive physiologic approach (i.e., the clinical evidence aligned from a micro- to macroscopic approach and vice versa).
DESIGN: Narrative review.
METHODS: Pubmed and Medline were used with the following key words: concussion and, physical activity, neurometabolic, gene regulation, trauma, nervous system, mild head injury, acute exercise, cellular physiology and pathophysiology.
CONCLUSION: It is our contention that understanding the cellular perspective will help guide clinical management, and promote research into post-concussion exercise.