Journal of toxicology. Clinical toxicology · 1998
Peripheral polyneuropathy due to chronic use of topical ammoniated mercury.
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Deleu D, Hanssens Y, al-Salmy H S, Hastie I
Аннотация
BACKGROUND: Despite their potentially disastrous side effects, topical mercury salts can still be found as ingredients in some over-the-counter preparations or local remedies.
CASE REPORT: Peripheral polyneuropathy as a result of chronic ammoniated mercury poisoning was studied and followed over 2 years. A 36-year-old man developed peripheral polyneuropathy following chronic perianal use of an ammoniated mercury ointment. Highly elevated blood and urine mercury levels were found. Sural nerve biopsy showed mixed axonal degeneration-demyelination. There was progressive improvement of his symptoms over 2 years but neurophysiological examination revealed incomplete recovery.
CONCLUSION: The availability of safer drugs should result in a complete ban of these dangerous compounds.
CASE REPORT: Peripheral polyneuropathy as a result of chronic ammoniated mercury poisoning was studied and followed over 2 years. A 36-year-old man developed peripheral polyneuropathy following chronic perianal use of an ammoniated mercury ointment. Highly elevated blood and urine mercury levels were found. Sural nerve biopsy showed mixed axonal degeneration-demyelination. There was progressive improvement of his symptoms over 2 years but neurophysiological examination revealed incomplete recovery.
CONCLUSION: The availability of safer drugs should result in a complete ban of these dangerous compounds.