A TICT-based fluorescent probe for rapid and specific detection of hydrogen sulfide and its bio-imaging applications.

By blocking the intramolecular twisted internal charge transfer (TICT) process, we designed and sythesized the first TICT-based fluorescent probe for hydrogen sulfide. The new probe exhibits high selectivity, good membrane-permeability and is suitable for visualization of exogenous and endogenous hydrogen sulfide in living cells.