[Effect of furosemide added to peritoneal dialysis fluid on hydroxyproline excretion in dialysate and urine].

The effect of furosemide (1500 mg/21 of peritoneal dialysis fluid) on excretion of hydroxyproline in dialysate and its renal clearance was investigated in 12 patients with end-stage renal disease on regular dialysis treatment. The 37 +/- 8% and 20 +/- 6% increase of D/S ratio of hydroxyproline after 5 and 8 hours of dwell, respectively, and 52 +/- 24% increase of renal clearance of hydroxyproline were induced by furosemide, which indicate its significant influence on peritoneal and renal removal of hydroxyproline.