Future oncology (London, England) · 2021
Direct costs of antineoplastic and supportive treatment for progressive multiple myeloma in a tax-based health system.
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Brøndum RF, Vestergaard AS, Børty L, Vesteghem C, Rytter AS, Nielsen MM, Severinsen MT, Jensen P, Gregersen H, El-Galaly TC, Dybkær K, Ehlers LH, Bøgsted M, Roug AS
Аннотация
Aim: To estimate current real-world costs of drugs and supportive care for the treatment of multiple myeloma in a tax-based health system. Methods: Forty-one patients were included from a personalized medicine study (2016-2019). Detailed information was collected from patient journals and hospital registries to estimate the total and mean costs using inverse probability weighting of censored data. Results: Total observed (censored) costs for the 41 patients was €8.84 million during 125 treatment years, with antineoplastic drugs as the main cost driver (€5.6 million). Individual costs showed large variations. Mean 3-year cost per patient from first progression was €182,103 (€131,800-232,405). Conclusion: Prediction of real-world costs is hindered by the availability of detailed costing data. Micro-costing analyses are needed for budgeting and real-world evaluation of cost-effectiveness.