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DOI 10.1007/s00406-026-02315-w

Медицинская библиотека · European archives of psychiatry and clinical neuroscience · 2026

Psychometric validation of research domain criteria, general health, and clinical-psychosocial parts of the minimum dataset of the German Center for Mental Health-informing a Delphi process.

Förstner Bernd R, Böttger Sarah Jane, Seegert Timm, Kerber André, Terhorst Yannik, Heinz Andreas, Dziobek Isabel, Voigt Babett, Schneider Silvia, Opel Nils, Walter Martin, Braun Urs, Meyer-Lindenberg Andreas, Koutsouleris Nikolaos, Falkai Peter, Schmitz Norbert, Fallgatter Andreas J, Sünkel Ulrike, Lipinski Silke, Rapp Michael A, Tschorn Mira, MDS Expert Group List

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Аннотация

OBJECTIVE

This study evaluated the latent structure and conceptual validity of the Research Domain Criteria (RDoC), General Health, and Clinical/Psychosocial clusters of the German Center for Mental Health (DZPG) Minimum Data Set (MDS). It aimed to determine whether these clusters represent interpretable constructs and demonstrate cross-group comparability across clinical and non-clinical populations, providing a data-driven basis for item selection within a Delphi consensus process.

METHODS

Two subsamples were analyzed: a representative sample (N = 2,287) and a clinic-recruited sample (N = 322) from six DZPG sites. Multi-group confirmatory factor analyses tested the latent structure and assessed configural, metric, and scalar measurement invariance between non-clinical vs. clinical/help-seeking groups.

RESULTS

All three MDS clusters demonstrated excellent baseline model fit (RDoC: CFI = .990, RMSEA = .037; General Health: CFI = .993, RMSEA = .037; Clinical/Psychosocial factors: CFI = .992, RMSEA = .026). Analyses confirmed configural and scalar invariance across all clusters but indicated non-invariance at the metric level for the General Health cluster.

CONCLUSIONS

The results provide initial evidence for the structural validity and cross-group comparability of the RDoC and Clinical/Psychosocial clusters, while indicating limitations regarding metric non-invariance within the General Health cluster. They informed a Delphi consensus process and support the MDS as a scalable framework for diverse populations, particularly relevant for the DZPG's effort to harmonize mental health data across institutions and contexts.

Для цитирования: Förstner Bernd R, Böttger Sarah Jane, Seegert Timm, Kerber André, Terhorst Yannik, Heinz Andreas, Dziobek Isabel, Voigt Babett, Schneider Silvia, Opel Nils, Walter Martin, Braun Urs, Meyer-Lindenberg Andreas, Koutsouleris Nikolaos, Falkai Peter, Schmitz Norbert, Fallgatter Andreas J, Sünkel Ulrike, Lipinski Silke, Rapp Michael A, Tschorn Mira, MDS Expert Group List. Psychometric validation of research domain criteria, general health, and clinical-psychosocial parts of the minimum dataset of the German Center for Mental Health-informing a Delphi process.. European archives of psychiatry and clinical neuroscience. 2026. DOI: 10.1007/s00406-026-02315-w.

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