Enhancing the resilience of remote patient monitoring and hospital-at-home systems: a digital-twin-based framework.

Remote patient monitoring (RPM) enables clinical oversight of patients outside the hospital via connected devices and supporting digital infrastructure. Hospital-at-home (HaH) is a high-acuity specialization within RPM. As RPM programs expand in scale and acuity, they face significant challenges to resilience that can compromise patient safety. We propose integrating simple patient Digital Twins (DTs), which are personalized models continuously updated with real-time data, to enhance the resilience of both HaH and RPM systems by supporting informed clinical management even when primary systems are unavailable, thereby improving patient safety during periods of network or other system unavailability.