[Use of catalytic properties of iron-containing salts in immunoanalysis].

The possibility of using inorganic catalysts as markers for solid-phase immunoassay on the plates is shown with iron-containing hydrosols: ferrum hydroxide, ammonium ferriglycerate, and ferrum hydroxide modified with potassium ferrocyanide. Diagnostic agents based on iron-containing sols with dispersion of 0.5 to 0.8 mm bound to immunoglobulins or staphylococcal protein A are no less sensitive than the immunoperoxidase agents, provided the same developing system is used (o-phenylenediamine + hydrogen peroxide). The sensitivity of solid-phase immunocatalytical assay of purified vaccinia and Venezuelan equine encephalomyelitis virus antigens was about 2 and 10 ng/ml, respectively. Hence, inorganic catalysts are prospective markers for immunoassay.