JACC. Advances · 2026
Trends in Cardiac Arrest Mortality Among Young Adults in the United States, 1999 to 2024.
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Shafiq Aimen, Ahmed Mushood, Zulfiqar Eeshal, Shahzad Maryam, Hashmi Tallal Mushtaq, Bhat Vivek, Greene Stephen J, Mentz Robert J, Fudim Marat, Rana Jamal S, Fonarow Gregg C, Kalra Ankur
Аннотация
BACKGROUND: Cardiac arrest (CA) affecting young individuals has been identified as a public health concern in the United States.
OBJECTIVES: This study analyzes mortality trends associated with CA in young adults in the United States, focusing on demographic and regional disparities.
METHODS: The Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research database was used to extract death certificate data for individuals aged 15 to 44 years from 1999 to 2024. Age-adjusted mortality rates (AAMRs) were determined, and annual percentage changes were generated using JoinPoint regression analysis.
RESULTS: From 1999 to 2024, a total of 289,237 deaths were attributed to CA among young individuals in the United States. The AAMR remained stable from 1999 to 2018 but experienced a significant rise between 2018 to 2021, annual percentage change: 16.50% (95% CI: 8.88%-19.87%), followed by a decline through 2024. Males consistently exhibited higher AAMRs than females (11.06 vs 7.33). Among racial and ethnic groups, non-Hispanic (NH) Black or African American individuals had the highest average AAMR (18.68), followed by Hispanic/Latino populations (7.92), NH White individuals (7.81), and NH other populations (6.00). Geographically, the Western region had the highest AAMR (10.47) in 2024, whereas rural areas consistently recorded higher AAMRs than urban areas (12.04 vs 8.30).
CONCLUSIONS: CA-related mortality in those aged 15 to 44 years exhibited fluctuating trends, with a notable rise between 2018 and 2021, followed by a decline through 2024. Males, NH Black Americans, and rural areas had higher mortality rates.
OBJECTIVES: This study analyzes mortality trends associated with CA in young adults in the United States, focusing on demographic and regional disparities.
METHODS: The Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research database was used to extract death certificate data for individuals aged 15 to 44 years from 1999 to 2024. Age-adjusted mortality rates (AAMRs) were determined, and annual percentage changes were generated using JoinPoint regression analysis.
RESULTS: From 1999 to 2024, a total of 289,237 deaths were attributed to CA among young individuals in the United States. The AAMR remained stable from 1999 to 2018 but experienced a significant rise between 2018 to 2021, annual percentage change: 16.50% (95% CI: 8.88%-19.87%), followed by a decline through 2024. Males consistently exhibited higher AAMRs than females (11.06 vs 7.33). Among racial and ethnic groups, non-Hispanic (NH) Black or African American individuals had the highest average AAMR (18.68), followed by Hispanic/Latino populations (7.92), NH White individuals (7.81), and NH other populations (6.00). Geographically, the Western region had the highest AAMR (10.47) in 2024, whereas rural areas consistently recorded higher AAMRs than urban areas (12.04 vs 8.30).
CONCLUSIONS: CA-related mortality in those aged 15 to 44 years exhibited fluctuating trends, with a notable rise between 2018 and 2021, followed by a decline through 2024. Males, NH Black Americans, and rural areas had higher mortality rates.