Journal of the American Heart Association · 2026
Long-Term Effect of Intensive Education in Patients With First-Ever Ischemic Stroke.
СтатьяМногоцентровое исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Kim Yeong Wook, Jeon Minsoo, Sohn Min Kyun, Lee Jongmin, Kim Deog Young, Oh Gyung-Jae, Lee Yang-Soo, Joo Min Cheol, Lee So Young, Song Min-Keun, Ko Sung-Hwa, Han Junhee, Ahn Jeonghoon, Shin Yong-Il, Lee Young-Hoon, Chang Won Hyuk
Аннотация
BACKGROUND: This study evaluated the long-term effects of intensive education on functional recovery and quality of life in patients with first-ever mild ischemic stroke.
METHODS: This propensity score-matched cohort study was conducted within the KOSCO (Korean Stroke Cohort for Functioning and Rehabilitation). Four of 9 institutions participated in the educational intervention substudy, recruiting patients between November 2016 and January 2020. Eligible participants were adults aged 19 to 74 years hospitalized within 7 days of a first-ever ischemic stroke, with mild neurological deficits (Korean version of National Institutes of Health Stroke Scale score 1-5), who consented to participate in the study. The intervention consisted of 3 structured education sessions delivered over 3 months. Functional and quality-of-life outcomes were assessed at baseline and at multiple intervals up to 48 months. A matched control group was selected from the primary KOSCO cohort.
RESULTS: After matching, 138 participants were included in each group. Baseline characteristics were well balanced. Over the 48-month follow-up period, the intervention group demonstrated greater improvements in the EuroQol-5 Dimension (β=-0.005 [95% CI, -0.009 to -0.001]), Geriatric Depression Scale-Short Form (β=0.147 [95% CI, 0.015-0.279]), and modified Rankin Scale (β=11.48 [95% CI, 0.05-22.92]), compared with controls. No significant group-by-time interactions were found for other functional measures, including the Functional Independence Measure, Korean version of Modified Barthel Index, Fugl-Meyer Assessment, and Korean Mini-Mental State Examination.
CONCLUSIONS: Structured, intensive, multisession education for patients with first-ever mild ischemic stroke produced favorable long-term effects on quality of life, psychological well-being, and disability, highlighting the value of comprehensive education as part of stroke rehabilitation and secondary prevention.
REGISTRATION: URL: http://cris.nih.go.kr; Unique identifier: KCT0003277.
METHODS: This propensity score-matched cohort study was conducted within the KOSCO (Korean Stroke Cohort for Functioning and Rehabilitation). Four of 9 institutions participated in the educational intervention substudy, recruiting patients between November 2016 and January 2020. Eligible participants were adults aged 19 to 74 years hospitalized within 7 days of a first-ever ischemic stroke, with mild neurological deficits (Korean version of National Institutes of Health Stroke Scale score 1-5), who consented to participate in the study. The intervention consisted of 3 structured education sessions delivered over 3 months. Functional and quality-of-life outcomes were assessed at baseline and at multiple intervals up to 48 months. A matched control group was selected from the primary KOSCO cohort.
RESULTS: After matching, 138 participants were included in each group. Baseline characteristics were well balanced. Over the 48-month follow-up period, the intervention group demonstrated greater improvements in the EuroQol-5 Dimension (β=-0.005 [95% CI, -0.009 to -0.001]), Geriatric Depression Scale-Short Form (β=0.147 [95% CI, 0.015-0.279]), and modified Rankin Scale (β=11.48 [95% CI, 0.05-22.92]), compared with controls. No significant group-by-time interactions were found for other functional measures, including the Functional Independence Measure, Korean version of Modified Barthel Index, Fugl-Meyer Assessment, and Korean Mini-Mental State Examination.
CONCLUSIONS: Structured, intensive, multisession education for patients with first-ever mild ischemic stroke produced favorable long-term effects on quality of life, psychological well-being, and disability, highlighting the value of comprehensive education as part of stroke rehabilitation and secondary prevention.
REGISTRATION: URL: http://cris.nih.go.kr; Unique identifier: KCT0003277.