[Resistance to the Venezuelan equine encephalomyelitis virus in immunization with live tularemia vaccine].

Guinea pigs immunized with live tularemia vaccine have been found to possess pronounced resistance to Venezuelan equine encephalomyelitis virus infection. Antiviral resistance induced by the vaccine has been found to persist for 1 month. One of the possible mechanisms, though not the only one, of this resistance is the stimulation of macrophages by tularemia vaccine, which results in the enhancement of their resistance to the cytotoxic action of the virus.