Advances in the DMSO reductase family: From discovery to mechanism.

DMSO reductase (DMSOR) family found in prokaryotes is the most diverse group of molybdenum cofactor (Moco) containing enzymes from the structural as well as the catalytic viewpoints. While DMSOR, the prototype member of its family, is well characterized thanks to decades of rigorous research, a large majority of this family are yet to be characterized. These enzymes are important in biogeochemical cycles, biotechnology and health. With the discovery of new DMSOR family members, the family continues to grow further underscoring their importance. This review will focus on the latest developments in the DMSOR reductase family.