Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology · 2011
Analgesic effect of Anatolian propolis in mice.
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Kamburoğlu Kıvanç, Özen Tuncer
Аннотация
OBJECTIVES: The aim of the present study was to assess the analgesic effect of Anatolian propolis, which is added to toothpastes as a prophylactic component for periodontal diseases.
METHODS: Water-, ethanol- and acetone-extracted Anatolian propolis were prepared. The analgesic effect of the extracts was assessed using the tail-flick test in mice (n=6 per extract). Comparison among groups was made using one-way ANOVA, followed by post-hoc Scheffe test to determine significant differences among the means of the data groups. P<0.05 was accepted as indicating a significant difference.
RESULTS: We found that water-extracted Anatolian propolis caused a significant increase, 1.61-fold (p<0.001 versus control), in the latency time using tail-flick test in mice. However, acetone-extracted and ethanol-extracted propolis led to no significant effect.
CONCLUSION: We proved the analgesic effect of water-extracted Anatolian propolis. Thus, propolis used in the composition of toothpastes may be beneficial in terms of its analgesic action in addition to its other favorable effects.
METHODS: Water-, ethanol- and acetone-extracted Anatolian propolis were prepared. The analgesic effect of the extracts was assessed using the tail-flick test in mice (n=6 per extract). Comparison among groups was made using one-way ANOVA, followed by post-hoc Scheffe test to determine significant differences among the means of the data groups. P<0.05 was accepted as indicating a significant difference.
RESULTS: We found that water-extracted Anatolian propolis caused a significant increase, 1.61-fold (p<0.001 versus control), in the latency time using tail-flick test in mice. However, acetone-extracted and ethanol-extracted propolis led to no significant effect.
CONCLUSION: We proved the analgesic effect of water-extracted Anatolian propolis. Thus, propolis used in the composition of toothpastes may be beneficial in terms of its analgesic action in addition to its other favorable effects.