Contemporary management of migraine, Part 2.

Prophylactic therapy is an important tool in the overall management of migraine. Established agents include beta blockers, methysergide, and TCAs. Other modalities, such as calcium channel blockers, NSAIDs, and biofeedback, may be useful when first-line therapy is ineffective. Understanding the use of abortive and prophylactic therapy of migraine will enable the pharmacist to play an important part in patient care.