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DOI 10.2147/imcrj.s558311

Медицинская библиотека · International medical case reports journal · 2026

Early-Onset Parkinson's Disease in a 36-Year-Old Woman with Uncomplicated Vaginal Birth: A Case Report.

Irapanussa Frans Arvindo, Santoso Dhanny Primantara Johari, Zulvayanti, Nisa Aisyah Shofiatun

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Аннотация

BACKGROUND

Parkinson's disease (PD) is a chronic neurodegenerative disorder that is rare in women of reproductive age, with limited literature describing pregnancy outcomes. Clinical management during gestation requires balancing symptom control with medication safety, while delivery planning should consider both neurological and obstetric factors.

CASE ILLUSTRATION: A 36-year-old woman, G4P3A0, at 36-37 weeks of gestation, presented with regular uterine contractions starting two hours prior to hospital admission. She had a 4-year history of Parkinson's disease and was on regular treatment with levodopa-benserazide HCL and trihexyphenidyl. Throughout the pregnancy, she attended regular antenatal visits to both the obstetric and neurology clinics. Vaginal delivery was planned in the absence of obstetric contraindications. Physical and obstetric examinations confirmed active phase of the first stage of labor. The patient underwent oxytocin augmentation with close monitoring. She delivered spontaneously via vaginal route, giving birth to a healthy female infant weighing 2645 grams with an APGAR score of 7-8. A Pomeroy sterilization procedure was performed postpartum. The patient was discharged in good condition and continued follow-up at the neurology clinic.

CONCLUSION

This case demonstrates that women in their 30s with PD can achieve favorable pregnancy outcomes, including uncomplicated vaginal delivery, when managed with close interdisciplinary collaboration. Continued reporting of similar cases is needed to strengthen the evidence base and guide clinical decision-making.

Для цитирования: Irapanussa Frans Arvindo, Santoso Dhanny Primantara Johari, Zulvayanti, Nisa Aisyah Shofiatun. Early-Onset Parkinson's Disease in a 36-Year-Old Woman with Uncomplicated Vaginal Birth: A Case Report.. International medical case reports journal. 2026. DOI: 10.2147/imcrj.s558311.
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