Journal of pharmacy & bioallied sciences · 2024
Effect of Different Pediatric Medications on RMGIC: A Comparative Study.
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Qurishi Ahtesham A, Al Dira Mohammed S, Sholan Amal H, Abzoah Shahad E, Hakami Mahdi A, Malhan Emad, Moafa Shahad M
Аннотация
INTRODUCTION: This study investigates the impact of commonly prescribed pediatric medications on resin-modified glass ionomer cement (RMGIC), which is widely used in pediatric dentistry in India. The interaction between these medications and RMGIC could affect the material's durability and effectiveness.
METHODOLOGY: Sixty RMGIC specimens were divided into five groups, each exposed to different pediatric medications: antibiotic syrup, antipyretic syrup, vitamin syrup, antitussive syrup, and distilled water (control). Microhardness and surface roughness were measured before and after a 14-day immersion period. Statistical analysis was conducted using one-way ANOVA and post-hoc Tukey's test.
RESULTS: All pediatric medications significantly affected RMGIC, with antitussive syrup showing the most substantial impact. Microhardness decreased by up to 18.40%, and surface roughness increased by up to 21.40%. The control group showed no significant changes.
CONCLUSION: Pediatric medications, particularly those with acidic properties, compromise the durability of RMGIC. Further research is needed to develop more resistant materials or protective measures.
METHODOLOGY: Sixty RMGIC specimens were divided into five groups, each exposed to different pediatric medications: antibiotic syrup, antipyretic syrup, vitamin syrup, antitussive syrup, and distilled water (control). Microhardness and surface roughness were measured before and after a 14-day immersion period. Statistical analysis was conducted using one-way ANOVA and post-hoc Tukey's test.
RESULTS: All pediatric medications significantly affected RMGIC, with antitussive syrup showing the most substantial impact. Microhardness decreased by up to 18.40%, and surface roughness increased by up to 21.40%. The control group showed no significant changes.
CONCLUSION: Pediatric medications, particularly those with acidic properties, compromise the durability of RMGIC. Further research is needed to develop more resistant materials or protective measures.