The Journal of laryngology and otology · 2026
Unveiling the impact of dengue fever on hearing health: a case control study.
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Soni Kapil, Agrawal Yash, Krishna M Swathi, Bohra Gopal, Goyal Amit, Sharma Vidhu
Аннотация
BACKGROUND: Dengue fever, a mosquito-borne viral illness, has varied systemic manifestations, but its auditory effects remain underexplored. The objective of this study was to assess the association between dengue infection and hearing loss.
METHODS: A prospective case-control study was conducted on 79 patients-40 dengue-positive (NS1 antigen confirmed) and 39 with other febrile illnesses. All participants underwent otological examination and pure tone audiometry.
RESULTS: Hearing loss was observed in 15.2 per cent of dengue patients, with none in controls (p < 0.001). The odds ratio for hearing loss in dengue was 34.6 (95 per cent confidence interval: 1.97-610). Dengue patients exhibited significantly elevated air and bone conduction thresholds (p < 0.001). Lower platelet counts and higher C-reactive protein levels correlated with hearing loss, suggesting vascular and inflammatory mechanisms.
CONCLUSION: Dengue fever may be associated with reversible sensorineural hearing loss, likely due to microvascular and inflammatory injury to the cochlea. Early audiological screening is recommended in dengue cases.
METHODS: A prospective case-control study was conducted on 79 patients-40 dengue-positive (NS1 antigen confirmed) and 39 with other febrile illnesses. All participants underwent otological examination and pure tone audiometry.
RESULTS: Hearing loss was observed in 15.2 per cent of dengue patients, with none in controls (p < 0.001). The odds ratio for hearing loss in dengue was 34.6 (95 per cent confidence interval: 1.97-610). Dengue patients exhibited significantly elevated air and bone conduction thresholds (p < 0.001). Lower platelet counts and higher C-reactive protein levels correlated with hearing loss, suggesting vascular and inflammatory mechanisms.
CONCLUSION: Dengue fever may be associated with reversible sensorineural hearing loss, likely due to microvascular and inflammatory injury to the cochlea. Early audiological screening is recommended in dengue cases.