Serum ferritin in the diagnosis of anemia during pregnancy.

Measurements of serum ferritin were correlated with bone marrow iron content and other laboratory hematological indices in 44 anemic (B-Hb < 110 g/l) pregnant women. Seventy-two % of patients classified as iron deficient by the absence of bone marrow iron had diagnostically low serum ferritin concentrations, which percentage is about double compared with those revealed by measurements of serum transferrin, TIBC, transferrin saturation, serum iron, blood hemoglobin and red cell indices. It is also important that serum ferritin was the only one of these measurements which was able to differentiate between iron deficiency, and anemia due to infection. Seven out of 8 patients with anemia due to infection had elevated serum ferritin levels. In 17% of patients no reason for the fall of blood hemoglobin could be shown. A plausible explanation for the low blood hemoglobin is extensive hemodilution.