Menopausal hormones and breast cancer in a biracial population.

OBJECTIVES

This study examined the association between menopausal hormones and breast cancer in a biracial population.

METHODS

Logistic regression was used to calculate odds ratios for breast cancer associated with hormone use among 397 cases and 425 controls, all menopausal women.

RESULTS

Odds ratios for ever use of hormones were 0.8 (95% confidence interval [CI] = 0.5, 1.2) for White women and 0.7 (95% CI = 0.4, 1.2) for Black women. Risk was not increased with longer duration of use or more recent use.

CONCLUSIONS

Breast cancer risk was not increased among White or Black women who used menopausal hormones, despite patterns of use varying considerably between races.