[Quantitative determination of secretory immunoglobulin A in the serum of patients with gynecologic tumors].

Secretory immunoglobulin A (S-IgA) was estimated by mean of single radial immunodiffusion and an antiserum against secretory component as well as an S-IgA standard in serum samples from 28 patients with fibroid, 18 patients with uterine cervix cancer, 8 patients with endometrium cancer and 4 patients with cancer of the vulva. 21 patients formed a control group. The average values were mean = 37,7 +/- 10,6 mg/l (control group), mean = 34,6 +/- 16,2 mg/l (fibroid), mean = 43,4 +/- 18,6 mg/l (uterine cervix cancer), mean = 43,3 +/- 20,0 mg/l (endometrium cancer). There were not significant differences between tumour groups and the control group. Some increased S-IgA values in the several groups were striking in the course of which we have not found any connection between the increased S-IgA values and the tumour stages as well as the histological tumour types. Moreover it was proved whether the posttherapeutical S-IgA values were changed in consequence of surgery or radiotherapy compared with values obtained before therapy values. Significant alterations were not ascertained with the t-test for compared observations.