A randomized comparison of three insemination methods in an artificial insemination program using husbands' semen.

OBJECTIVE

To compare pregnancy rates with single intrauterine insemination (SIUI), double intrauterine insemination (DIUI) and fallopian tube sperm perfusion (FSP).

STUDY

DESIGN

Ninety patients undergoing a standard ovarian stimulation regimen were randomized to receive SIUI, DIUI or FSP. The end point was either pregnancy or completion of 3 treatment cycles without pregnancy.

RESULTS

There were no differences in demographic data or ovarian responses. The total number of motile spermatozoa inseminated in the FSP group was significantly lower than in the SIUI group. No significant differences were found in pregnancy rate per cycle or patient, multiple pregnancy rate and outcome of pregnancy between the 3 groups.

CONCLUSION

Similar pregnancy rates were achieved after SIUI, DIUI and FSP during stimulated cycles.