Percutaneous vasal sperm aspiration and intrauterine insemination for infertile males with anejaculation.

OBJECTIVE

To explore the effectiveness of percutaneous vasal sperm aspiration (PVSA) in combination with intrauterine insemination (IUI) to treat infertile men with anejaculation.

DESIGN

Clinical study.

SETTING

Department of reproductive endocrinology and andrology of a family planning research clinic.

PATIENT(S): Twenty-six anejaculatory infertile men.

INTERVENTION(S): Spermatozoa obtained from the vas deferens by percutaneous aspiration were incubated in sperm preparation medium.

MAIN OUTCOME MEASURE(S): Sperm quality by PVSA and pregnancy outcome.

RESULT(S): Thirty-four PVSA-IUI procedures were performed in 26 men with anejaculation. Nineteen pregnancies were achieved (pregnancy rate, 73.1%). Mean (+/-SD) values for sperm variables were as follows: motility, 78.6% +/- 14.2%; progressive motility, 60.4% +/- 11.2%; density, 37.6 +/- 13.2 x 10(6) cells/mL; total count, 35.2 +/- 13.2 x 10(6) cells; and abnormal sperm, 18.6% +/- 7.6%.

CONCLUSION(S): Percutaneous vasal sperm aspiration may obtain high-motility sperm, and PVSA plus IUI is an effective treatment for male infertility with anejaculation.