Fertility and sterility · 1997
A comparison of clomiphene citrate and human menopausal gonadotropin for use in conjunction with intrauterine insemination.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Manganiello P D, Stern J E, Stukel T A, Crow H, Brinck-Johnsen T, Weiss J E
Аннотация
OBJECTIVE: To compare the outcome of superovulation using clomiphene citrate (CC) versus hMG in conjunction with IUI.
DESIGN: Sequentially assigned, observational study. Couples initially were assigned to receive either CC or hMG for three cycles.
SETTING: The Clinical Outpatient Department of the Dartmouth-Hitchcock Medical Center.
PATIENT(S): Eighty-three infertile couples.
INTERVENTION(S): IUI with hMG use.
MAIN OUTCOME MEASURE(S): Conception rate, term pregnancy rate (PR), and pregnancy complications, such as spontaneous miscarriage and multiple gestation.
RESULT(S): Of 83 couples who underwent at least one treatment cycle, 29 (35%) conceived during the study period. The relative rate of conception for hMG versus CC was 2.08 (95% confidence interval [CI], 0.93 to 4.68). The relative term PR was 2.10 (95% CI, 0.77 to 5.73) for hMG versus CC. There was no difference in the miscarriage rate for hMG versus CC.
CONCLUSION(S): Both the conception rate and the term PR were higher using hMG, compared with CC, in combination with IUI, and showed a trend toward statistical significance.
DESIGN: Sequentially assigned, observational study. Couples initially were assigned to receive either CC or hMG for three cycles.
SETTING: The Clinical Outpatient Department of the Dartmouth-Hitchcock Medical Center.
PATIENT(S): Eighty-three infertile couples.
INTERVENTION(S): IUI with hMG use.
MAIN OUTCOME MEASURE(S): Conception rate, term pregnancy rate (PR), and pregnancy complications, such as spontaneous miscarriage and multiple gestation.
RESULT(S): Of 83 couples who underwent at least one treatment cycle, 29 (35%) conceived during the study period. The relative rate of conception for hMG versus CC was 2.08 (95% confidence interval [CI], 0.93 to 4.68). The relative term PR was 2.10 (95% CI, 0.77 to 5.73) for hMG versus CC. There was no difference in the miscarriage rate for hMG versus CC.
CONCLUSION(S): Both the conception rate and the term PR were higher using hMG, compared with CC, in combination with IUI, and showed a trend toward statistical significance.