Evaluation of predictive factors for multiple pregnancies during gonadotropin/IUI treatment.

PURPOSE: Our purpose was to analyze factors for their predictability of multiple pregnancies in patients treated with a combination of human menopausal gonadotropins (hMG) and intrauterine insemination (IUI).

METHODS

The records of all patients conceiving through treatment with hMG/IUI were reviewed for factors predictive of multiple pregnancy.

RESULTS

Ninety-one pregnancies reviewed included 78 singleton (86%), 8 twin (9%), and 5 higher-order pregnancies (5%). The total number of follicles > 10 mm was greater in the multiple-pregnancy group and there was a decreased number of postwash sperm in the multiple-pregnancy group. Otherwise there was no significant difference in the factors analyzed.

CONCLUSIONS

No factor or combination of factors predicts multiple pregnancies to a degree that it would be helpful in managing or counseling patients.