Spontaneous pregnancy in couples waiting for artificial insemination donor because of severe male infertility.

OBJECTIVE

To assess the spontaneous fertility in couples with severe seminal conditions while waiting for artificial insemination donor.

STUDY

DESIGN

Prospective follow-up during a period of 24 months.

SETTING

University Medical School.

PARTICIPANTS

There were 285 couples in which the male had a very severe seminal pathology: 166 azoospermia, 86 oligozoospermia and 33 severe asthenozoospermia.

OUTCOME MEASURES: Pregnancy rates after being included on waiting list.

RESULTS

The spontaneous pregnancy rate was 3.2% (9/285), per month spontaneous pregnancy rate being 0.13%. Spontaneous pregnancy rate was 0% in azoospermia (0/166). versus 7.6% (9/119) in non-azoospermia cases. Spontaneous pregnancy rate was 8.5% (4/47) in the group with less than 0.1 million motile sperm/cc, 6.5% (3/46) in the group between 0.1 and 1 million/cc and 7.7% (2/26) in the group with 1-2 million/cc.

CONCLUSION

In a 2-year follow-up, pregnancy rate among non-azoospermic couples before undergoing artificial insemination was 7.6%. Extramatrimonial pregnancy (based on anamnesis and sperm analysis) seemed to be uncommon. Even in cases with less than 0.1 million of motile sperm/cc there was not a negligible spontaneous pregnancy rate.