European journal of obstetrics, gynecology, and reproductive biology · 1996
Evaluation of the postcoital test for assessment of 'cervical factor' infertility.
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Oei S G, Bloemenkamp K W, Helmerhorst F M, Naaktgeboren N, Keirse M J
Аннотация
OBJECTIVE: To evaluate the test properties of the postcoital test (PCT).
STUDY DESIGN: Retrospective analysis of prospectively collected data on a cohort of infertile couples with complete follow up.
SETTING: Fertility clinic of a Dutch university hospital.
SUBJECTS: A continuous series of 224 couples of whom 24 were excluded for reasons of anovulation, coital problems, proven sterility or incomplete follow-up.
ANALYSIS: Cumulative pregnancy rates in relation to PCT results with and without treatment for 'cervical factor' infertility.
RESULTS: The predictive values of normal and abnormal PCTs were 0.54 and 0.58 overall and 0.74 and 0.47 if only untreated women were considered. Sensitivity and specificity were, respectively, 0.47 and 0.65 for all women and 0.54 and 0.68 for untreated women only. Likelihood ratios for normal and abnormal PCTs were 0.83 and 1.32 overall and 0.67 and 1.72 in untreated women.
CONCLUSION: The PCT has poor predictive power. This and the psychological impact on subfertile couples attest to the need for more rigorous study designs in evaluating this test.
STUDY DESIGN: Retrospective analysis of prospectively collected data on a cohort of infertile couples with complete follow up.
SETTING: Fertility clinic of a Dutch university hospital.
SUBJECTS: A continuous series of 224 couples of whom 24 were excluded for reasons of anovulation, coital problems, proven sterility or incomplete follow-up.
ANALYSIS: Cumulative pregnancy rates in relation to PCT results with and without treatment for 'cervical factor' infertility.
RESULTS: The predictive values of normal and abnormal PCTs were 0.54 and 0.58 overall and 0.74 and 0.47 if only untreated women were considered. Sensitivity and specificity were, respectively, 0.47 and 0.65 for all women and 0.54 and 0.68 for untreated women only. Likelihood ratios for normal and abnormal PCTs were 0.83 and 1.32 overall and 0.67 and 1.72 in untreated women.
CONCLUSION: The PCT has poor predictive power. This and the psychological impact on subfertile couples attest to the need for more rigorous study designs in evaluating this test.