Reverse Takotsubo Syndrome in Women During High Hormonal States Related to In Vitro Fertilization.

Takotsubo syndrome (TTS) has heterogenous clinical presentations for which the pathophysiologic mechanisms remain incompletely understood. Identifying patterns to the variants of TTS, including reverse TTS, may provide insight into TTS pathophysiology. In this report, we share 3 cases of reverse TTS in premenopausal women at different stages of in vitro fertilization, suggesting a link between heightened hormonal states and midbasal left ventricular dysfunction in the setting of TTS.