[Preimplantation genetic diagnosis].

BACKGROUND

The revised Norwegian biotechnology law implies restrictive use of preimplantation genetic diagnostics--a highly specialised procedure, which is still in an early phase of development.

MATERIAL AND METHOD: The paper is based on more than 10 years of clinical experience in preimplantation genetic diagnostics and on literature retrieved through PubMed/Medline.

RESULTS

According to the biotechnology law, preimplantation genetic diagnostics can only be carried out when strict medical indications are present. Genetic counselling and a fertility work-up are compulsory for couples who wish to receive preimplantation genetic diagnostics.

INTERPRETATION: Few disorders have an indication for preimplantation genetic diagnostics. It will therefore take time to build up adequate national expertise. For couples with a known risk of serious hereditary disease, preimplantation genetic diagnosis is useful in achieving an uncomplicated pregnancy and a healthy child.