Genetic counselling for schizophrenia in the era of molecular genetics.

OBJECTIVE

To review the role of genetic counselling for individuals with psychiatric illnesses.

METHOD: Using schizophrenia as an example and including updated information about a genetic subtype (22q deletion syndrome), we discuss the value of the genetic counselling process in psychiatry, with support from the literature and our clinical experience.

RESULTS

Genetic counselling, the process through which knowledge about the genetics of illnesses is shared, provides information on the inheritance of illnesses and their recurrence risks; addresses the concerns of patients, their families, and their health care providers; and supports patients and their families dealing with these illnesses. For comprehensive medical management, this service should be available to all individuals with schizophrenia and their families.

CONCLUSIONS

New findings in the genetics of psychiatric illness may have important clinical implications for patients and their families.