Multiple myeloma.

OBJECTIVES

To review the epidemiology, pathogenesis, clinical features, diagnosis, treatment, and nursing management of multiple myeloma.

DATA SOURCES: Review articles, research studies, and book chapters related to multiple myeloma.

CONCLUSIONS

Despite insights into the immunobiology of multiple myeloma and the advances in intensive therapy and supportive care, multiple myeloma remains an incurable disease. Patients will experience chronic and acute symptomatic episodes throughout the course of their disease.

IMPLICATIONS FOR NURSING PRACTICE: Oncology nurses can assist patients with multiple myeloma and their families to manage both the disease and treatment related symptoms and to improve their overall quality of life. Specific nursing assessments can provide early recognition of complications, such as hypercalcemia and spinal cord compression.