In vitro optical characterization of the RayOne Galaxy spiral extended depth-of-focus intraocular lens using high-resolution Mach-Zehnder interferometry.

Spiral optics have been proposed to extend depth of focus through controlled phase modulation. We characterized the RayOne Galaxy spiral intraocular lens using high-resolution Mach-Zehnder interferometry and a simulated pseudophakic Arizona eye model. Wavefronts were decomposed into Zernike polynomials and compared with monofocal, trifocal, and spherical-aberration-based extended-depth-of-focus (EDOF) lenses. The Galaxy exhibited a smooth EDOF profile with a moderate reduction in contrast rendering. Symmetry analysis showed that radially symmetric aberrations primarily generated the EDOF effect, while the spiral component played a secondary role.