Journal of clinical practice and research · 2026
Limbic System Glioblastoma Extending to the Papez Circuit: A Case Report.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Kıcıklar Sena, Fırat Zeynep, Ekinci Gazanfer
Аннотация
BACKGROUND: Glioblastoma is the most common malignancy of the central nervous system. Symptoms vary significantly depending on tumor location and size.
CASE REPORT: A 55-year-old man presented with mild memory deficits, occasional eye twitching, and throat irritation for two months. Magnetic resonance imaging revealed a glioma centered in the piriform cortex, infiltrating the amygdala, hippocampus, bilateral fornices, mammillary bodies, anterior cingulate gyrus, and anterior commissure.
CONCLUSION: Despite extensive involvement of the limbic system and the Papez circuit, the patient exhibited a remarkable paucity of symptoms and maintained his daily functioning. This discrepancy was elucidated by diffusion tensor imaging tractography, which demonstrated that the tumor primarily displaced, rather than destroyed, the adjacent white matter tracts.
CASE REPORT: A 55-year-old man presented with mild memory deficits, occasional eye twitching, and throat irritation for two months. Magnetic resonance imaging revealed a glioma centered in the piriform cortex, infiltrating the amygdala, hippocampus, bilateral fornices, mammillary bodies, anterior cingulate gyrus, and anterior commissure.
CONCLUSION: Despite extensive involvement of the limbic system and the Papez circuit, the patient exhibited a remarkable paucity of symptoms and maintained his daily functioning. This discrepancy was elucidated by diffusion tensor imaging tractography, which demonstrated that the tumor primarily displaced, rather than destroyed, the adjacent white matter tracts.