Bilateral ovarian abscesses following platelet-rich plasma injection for "ovarian rejuvenation": a case report.

OBJECTIVE

To describe a case of severe infectious complications following ovarian platelet-rich plasma (PRP) injections for ovarian rejuvenation.

DESIGN

Case report.

SUBJECTS: A 45-year-old nulligravid woman with a history of uterine fibroids and ovarian cysts presenting to an academic medical center.

EXPOSURE: Ovarian PRP injections were performed at an outside facility. Following presentation, the patient was treated with intravenous antibiotics. Because of persistent symptoms and clinical deterioration, she subsequently underwent image-guided aspiration of bilateral tubo-ovarian abscesses.

MAIN OUTCOME MEASURES: Resolution of infection and resumption of baseline activity and menstrual cycles.

RESULTS

The patient presented with persistent lower abdominal pain, leukocytosis, and complex bilateral adnexal masses on imaging several days after intraovarian PRP injection. Cultures from aspirated abscesses grew Streptococcus anginosus. After treatment, she achieved full clinical recovery, resuming normal menses and activity within four months.

CONCLUSION

Ovarian PRP injections, although increasingly marketed for "rejuvenation," carry risks of severe complications, including infection, such as tubo-ovarian abscess formation. This case underscores the need for caution and further investigation into the safety and efficacy of PRP for reproductive indications.