Commercially Pure Titanium Implants With Selenium and Hyaluronic Acid Coating for Dental Applications.

Background The current study demonstrated improved efficiency of commercially pure titanium (CP-Ti) dental implants with a biocompatible coating of selenium (Se) and hyaluronic acid (HA).  Methods The sol-gel solution was made with hyaluronic acid and selenium nitrate in a 1:1 ratio. The coating sample was subjected to characterization studies such as Fourier Transform Infrared (FTIR) spectroscopy, surface morphology analysis, contact angle, etc., to confirm the coating. The antimicrobial activity of the coating was studied by analyzing the zone of inhibition. Results The FTIR spectroscopy was analyzed to confirm the functional groups of Se/HA. The surface morphology of the coated sample appeared as tiny needles with a plate-like surface. The potentiodynamic polarization studies revealed that the coated Ti samples exhibit superior corrosion resistance. The antimicrobial activity of Staphylococcus aureus was found to be more effective at a concentration of 100 mg. Furthermore, the basic criteria of biomaterials were analyzed for hemocompatibility studies, which suggested a non-hemolytic character. Conclusion The biocompatible coating of Se and HA has proven to be of superior corrosion resistance and antimicrobial activity resistance, which validate the usage of dental implants.