Journal of pediatric and adolescent gynecology · 2024
Mesalamine as Treatment of Neovaginal Ileitis: Case Report and Review of Literature.
СтатьяКлинический случайОбзорНазвание и аннотация: Перевод в очереди
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King-Nakaoka Elana A, Yu Lissa X
Аннотация
BACKGROUND: Neovaginal ileitis is an understudied complication of intestinal vaginoplasty for which no evidence-based treatments exist. Mesalamine has been successfully reported to treat neovaginal colitis and has mixed evidence of efficacy in treating ileal inflammatory syndromes.
CASE: We report a 29-year-old female with a history of ileal neovaginoplasty at 2 years of age for cloacal variant and treatment-refractory neovaginal ileitis with pain and bleeding whose symptoms resolved with treatment with topical mesalamine.
CONCLUSION: Mesalamine may be a viable treatment for neovaginal ileitis. More data is needed on neovaginal ileitis incidence and treatment, in addition to broader quality of life outcomes after intestinal vaginoplasty.
CASE: We report a 29-year-old female with a history of ileal neovaginoplasty at 2 years of age for cloacal variant and treatment-refractory neovaginal ileitis with pain and bleeding whose symptoms resolved with treatment with topical mesalamine.
CONCLUSION: Mesalamine may be a viable treatment for neovaginal ileitis. More data is needed on neovaginal ileitis incidence and treatment, in addition to broader quality of life outcomes after intestinal vaginoplasty.