Allergology international : official journal of the Japanese Society of Allergology · 2025
Association between yellow dust, PM2.5, and hay fever: A large-scale crowdsourced observational study using the AllerSearch smartphone application.
СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод в очереди
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Nagino Ken, Inomata Takenori, Ebihara Nobuyuki, Midorikawa-Inomata Akie, Fujio Kenta, Kobayashi Hiroyuki, Nakao Shintaro
Аннотация
BACKGROUND: This large-scale crowdsourced observational study investigated the association between yellow dust, particulate matter 2.5 (PM2.5), and hay fever symptoms using the AllerSearch smartphone application.
METHODS: Participants with hay fever were divided into four groups based on combinations of high and low pollen and PM2.5/yellow dust dispersion levels. Nine hay fever symptom scores and quality of life (QoL) scores were compared among the groups. Multivariate analysis evaluated independent associations between pollen and PM2.5/yellow dust dispersion levels and hay fever symptom and QoL scores. Risk factors for individuals experiencing worsening hay fever symptoms during PM2.5/yellow dust dispersion were evaluated using multivariate logistic regression analysis.
RESULTS: This analysis included 6468 participants. All hay fever symptom scores except "ear and/or mouth itching," and all QoL scores were significantly higher in the "low pollen and moderate-to-high PM2.5/yellow dust" group versus the "low pollen and low PM2.5/yellow dust" group. PM2.5/yellow dust levels independently associated with worsening of hay fever symptom and QoL scores, except for "ear and/or mouth itching." Being a woman (P = 0.010), a history of atopic dermatitis (P = 0.013), bronchial asthma (P = 0.046), dry eye disease (P = 0.048), oral medication (P = 0.009) and air purifier use (P = 0.043) were significant risk factors for worsening hay fever symptoms during PM2.5/yellow dust dispersion.
CONCLUSIONS: Our findings suggest that PM2.5 and yellow dust exacerbated hay fever symptoms independent of pollen exposure, with distinct symptom profiles.
METHODS: Participants with hay fever were divided into four groups based on combinations of high and low pollen and PM2.5/yellow dust dispersion levels. Nine hay fever symptom scores and quality of life (QoL) scores were compared among the groups. Multivariate analysis evaluated independent associations between pollen and PM2.5/yellow dust dispersion levels and hay fever symptom and QoL scores. Risk factors for individuals experiencing worsening hay fever symptoms during PM2.5/yellow dust dispersion were evaluated using multivariate logistic regression analysis.
RESULTS: This analysis included 6468 participants. All hay fever symptom scores except "ear and/or mouth itching," and all QoL scores were significantly higher in the "low pollen and moderate-to-high PM2.5/yellow dust" group versus the "low pollen and low PM2.5/yellow dust" group. PM2.5/yellow dust levels independently associated with worsening of hay fever symptom and QoL scores, except for "ear and/or mouth itching." Being a woman (P = 0.010), a history of atopic dermatitis (P = 0.013), bronchial asthma (P = 0.046), dry eye disease (P = 0.048), oral medication (P = 0.009) and air purifier use (P = 0.043) were significant risk factors for worsening hay fever symptoms during PM2.5/yellow dust dispersion.
CONCLUSIONS: Our findings suggest that PM2.5 and yellow dust exacerbated hay fever symptoms independent of pollen exposure, with distinct symptom profiles.