[Clinical and immunological effect of washing powder enzymes on workers and users (author's transl)].

For 141 workers in the washing powder industry in Maribor (Group A) and 68 workers of vegetables' shops to determine the risk of sensitization for house-wives handling enzymes detergents (Group B) as a control group the results of diagnostic investigations as well as analyses of protective measures to proteolytic enzymes are contrasted. Within the Group A eight subgroups according to exposition to proteolytic enzymes powder are evaluated. Especially elucited are the results of skin testing (Scratch-tets with Maxatase, Alcalase and culture extract from B. subtilis) and with proteolytic enzymes powder, the lung function tests (vitalogram, spirogram, pneumometer-test diffusion-test and sometimes the blood gas tests), cytological examinations of nasal mucosa and simultaneously taking a blood sample for determination of concentration of total serum IgE and precipitins to enzymes extracts.