Резюме ежегодного совещания Университета медицины и фармацевтики: 4th - 8th декабрь 2023, Клюй-Напока
Аннотация
Аннотация не предоставлена источником. Содержательный обзор этой публикации недоступен.
Название и аннотация на языке оригинала
Abstracts of the Annual Meeting of the ”Iuliu Haţieganu” University of Medicine and Pharmacy : 4th – 8th December 2023, Cluj-Napoca
Полный текст на русском
Машинный перевод · не проверен
Наше исследование было направлено на оценку воздействия смесей натуральных продуктов в модели AD-подобных животных. Химический анализ смесей натуральных продуктов проводился с помощью спектрометрических и хроматографических методов (LC-MS). Цели этих природных соединений включали различные патологические механизмы в АД, такие, как продукты окисления, провокационные пути и выражение белков мозга. Результаты химического анализа смесей натуральных продуктов свидетельствуют о наличии большого количества хлоргенных, трансп-кумарных кислот, гекцетола и курица, которые оказались полезными для вышеупомянутых механизмов.Выводы, сделанные нами, свидетельствуют о том, что природные продукты, смешанные с различными фармакологическими видами деятельности, могут играть важную роль в обнаружении наркотиков АД.
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Introduction
Our study aimed to evaluate the effects of natural products mixtures in an AD-like animal model.
Material and methods
The chemical analysis of the natural products mixtures was performed by spectrophotometric and chromatographic methods (LC-MS). The targets of these natural compounds included different pathological mechanisms in AD, such as, oxidation products, inflammatory pathways and brain proteins expression.
Results
The chemical analyzes of the natural products mixtures revealed high amounts of chlorogenic, trans-p-coumaric acids, quercetol and quercitin, which have proven to have beneficial on the above mentioned mechanisms.
Conclusion
Our findings indicate that natural products mixtures with various pharmacological activities may play a relevant role in the AD drug discovery.
Подготовка и перевод публикации
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Тип публикации указан по данным источника. Уровень доказательности автоматически не присваивается.