Медицинская библиотека · Emerging infectious diseases · 2010

Pandemic (H1N1) 2009 infection in patients with hematologic malignancy.

Liu C, Schwartz BS, Vallabhaneni S, Nixon M, Chin-Hong PV, Miller SA, Chiu C, Damon L, Drew WL

Перевод в очереди

Аннотация

To assess outcomes of patients with hematologic malignancy and pandemic (H1N1) 2009 infection, we reviewed cases during June-December 2009 at the University of California San Francisco Medical Center. Seventeen (63%) and 10 (37%) patients had upper respiratory tract infection (URTI) and lower respiratory tract infection (LRTI), respectively. Cough (85%) and fever (70%) were the most common signs; 19% of patients had nausea, vomiting, or diarrhea. Sixty-five percent of URTI patients were outpatients; 35% recovered without antiviral therapy. All LRTI patients were hospitalized; half required intensive care unit admission. Complications included acute respiratory distress syndrome, pneumomediastinum, myocarditis, and development of oseltamivir-resistant virus; 3 patients died. Of the 3 patients with nosocomial pandemic (H1N1) 2009, 2 died. Pandemic (H1N1) 2009 may cause serious illness in patients with hematologic malignancy, primarily those with LRTI. Rigorous infection control, improved techniques for diagnosing respiratory disease, and early antiviral therapy can prevent nosocomial transmission and optimize patient care.

Для цитирования: Liu C, Schwartz BS, Vallabhaneni S, Nixon M, Chin-Hong PV, Miller SA, Chiu C, Damon L, Drew WL. Pandemic (H1N1) 2009 infection in patients with hematologic malignancy.. Emerging infectious diseases. 2010. DOI: 10.3201/eid1612.100772.

Перевод полного текста: Перевод в очереди

Полный текст источника

https://creativecommons.org/licenses/by/4.0/ This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. https://creativecommons.org/licenses/by/4.0/ This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. https://creativecommons.org/licenses/by/4.0/ This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.

MEDSCAPE CME

Medscape, LLC is pleased to provide online continuing medical education (CME) for this journal article, allowing clinicians the opportunity to earn CME credit. This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of Medscape, LLC and Emerging Infectious Diseases. Medscape, LLC is accredited by the ACCME to provide continuing medical education for physicians. Medscape, LLC designates this educational activity for a maximum of 0.5 AMA PRA Category 1 Credits ™. Physicians should only claim credit commensurate with the extent of their participation in the activity. All other clinicians completing this activity will be issued a certificate of participation. To participate in this journal CME activity: (1) review the learning objectives and author disclosures; (2) study the education content; (3) take the post-test and/or complete the evaluation at www.medscapecme.com/journal/eid ; (4) view/print certificate.

Learning Objectives

Upon completion of this activity, participants will be able to:

Distinguish the most common presenting symptom of pandemic (H1N1) 2009 infection in the current study

Analyze the course of lower respiratory tract infection with pandemic (H1N1) 2009 among patients with hematologic malignancy

Develop appropriate management strategies for pandemic (H1N1) 2009 infection for patients with hematologic malignancy

Medscape CME Editor

Karen L. Foster, MA , Technical Writer-Editor, Emerging Infectious Diseases. Disclosure: Karen L. Foster, MA, has disclosed no relevant financial relationships.

Medscape CME AUTHOR

Charles P. Vega, MD , Associate Professor; Residency Director, Department of Family Medicine, University of California, Irvine. Disclosure: Charles P. Vega, MD, has disclosed no relevant financial relationships.

AUTHORS

Disclosures: Catherine Liu, MD; Brian S. Schwartz, MD; Snigdha Vallabhaneni, MD; Michael Nixon, NP; Peter V. Chin-Hong, MD Steven A. Miller, MD, PhD; and W. Lawrence Drew, MD, PhD , have disclosed no relevant financial relationships. Charles Chiu, MD, PhD, has disclosed the following relevant financial relationship: served as a speaker or a member of a speakers bureau for Cubist Pharmaceuticals, Inc. Lloyd Damon, MD, has disclosed the following relevant financial relationships: served as a speaker or a member of a speakers bureau for Celgene Corporation; Eisai Inc.; owns stock, stock options, or bonds from Genentech, Inc.

Suggested citation for this article: Liu C, Schwartz BS, Vallabhaneni S, Nixon M, Chin-Hong PV, Miller SA, et al. Pandemic (H1N1) 2009 infection in patients with hematologic malignancy. Emerg Infect Dis [serial on the Internet]. 2010 Dec [ date cited ]. http://dx.doi.org/10.3201/eid1612.100772

Подготовка и перевод публикации

Обработка статьи · этапы, ошибки и управление

Загрузка состояния…

История · было → стало

Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.