Eletrophysiological study of the caudal nerve on developing rats.

PURPOSE: To non-invasively study the sensory nerve conduction of the caudal nerve of normal developing rats.

METHODS

Twenty normal Wistar male rats served as subjects. Caudal nerve conduction studies were performed at 60 days from birth and weekly at end of six consecutive weeks. The caudal nerve was stimulated distally and nerve potentials were recorded proximally on the animal's tail using common 'alligator' clips as surface electrodes.

RESULTS

The amplitude and the conduction velocity of the caudal nerve sensory action potential increased linearly from 29+/-6 microV to 85+/-13 microV and from 34+/-3 m/s to 44+/-4 m/s, respectively, between the 8th and the 15th week of life. The equations of linear regressions were as followed: Amplitude (microV) = 8.1 x weeks - 34 (R(2) = 0.99) and NCV (m/s) = 1.2 x weeks + 25 (R(2) = 0.86).

CONCLUSIONS

It was possible to study non-invasively the sensitive conduction of the caudal nerve of normal developing rats and describe reference values. The technique and data may be used as animal model in physiological and pathological studies.