Ten-year experience with stentless aortic valves: full-root versus subcoronary implantation.

BACKGROUND: We compared the midterm outcome after aortic valve replacement with the Freestyle stentless bioprosthesis for the full-root or subcoronary implantation technique, while adjusting for patient and disease characteristics by a propensity score.

METHODS: Between 1996 and 2005, 1,014 patients underwent aortic valve replacement with the stentless Medtronic Freestyle bioprosthesis, 168 using full-root technique. Based on a saturated propensity score, 148 matched pairs were created. Mean age of the 296 patients was 73 +/- 3 years. Mean follow-up time was 32 +/- 30 months (maximum, 116 months).

RESULTS: Operative mortality was 4.7% and 2.7% (p = 0.36) in the full-root and subcoronary groups, respectively. Freedom from reoperation, prosthetic valve endocarditis, major bleeding, and thromboembolism after 9 years was 98% +/- 1% and 90% +/- 7% (p = 0.38), 95% +/- 3% and 92% +/- 7% (p = 0.76), 72% +/- 21% and 98% +/- 2% (p = 0.12), and 75% +/- 8% and 84% +/- 7% (p = 0.28), for full-root and subcoronary groups, respectively. Survival rates after 9 years were 34% +/- 24% and 33% +/- 11% (p = 0.46), for the full-root and subcoronary groups, respectively. Patients in the full-root group received larger valve sizes (p = 0.03), and the mean transprosthetic gradients at discharge were significantly lower for each valve size. Nevertheless, during follow-up, peak gradients decreased to a greater extent in patients presenting high peak gradients (>36 mm Hg) at discharge.

CONCLUSIONS: As risk-adjusted comparison of both implantation techniques did not reveal any differences regarding operative and midterm outcomes, full-root replacement can be liberally performed in patients with small aortic roots, annuloaortic ectasia, or requiring replacement of ascending aorta.