Journal of cosmetic dermatology · 2025
Hydrogel-Based Therapies for Photoaging: Current Advances and Future Perspectives.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Gao Qiong, Xu Chenghong, Tan Mingwei, Wang Yucheng, Liu YiDing, Wang Yifeng, Fan Yibin, Tao Xiaohua, Lu Wei, Huang Youming, Teng Yan
Аннотация
BACKGROUND: Photoaging, caused by long-term ultraviolet (UV) exposure, leads to wrinkles, loss of skin elasticity, pigmentation disorders, and impaired barrier function due to oxidative stress, DNA damage, and collagen breakdown. Hydrogels, with their high water content (> 90%), biocompatibility, and controlled drug release capabilities, have emerged as a powerful tool for preventing and treating skin photoaging.
AIMS: To review current treatment strategies and provide an updated perspective on the treatment of photoaging.
METHODS: We searched the PubMed and Web of Science library databases for eligible studies published within the past 5 years, categorizing and evaluating the effects of hydrogels with different carriers and active ingredients.
RESULTS: A total of 21 relevant studies were included, involving Lipid-based Hydrogels, Hyaluronic Acid-based Hydrogels, Chitosan-based Hydrogels, Polyacrylonitrile-modified κ-Carrageenan-based Hydrogels, Gellan Gum/Sodium Alginate-based Hydrogels, Recombinant Collagen-based Hydrogels, and Other Polymer-based Hydrogels.
CONCLUSIONS: The collected studies consistently demonstrate that hydrogel therapy is more effective than traditional treatments in reducing UV-induced skin damage and promoting skin repair and regeneration. In addition to improving drug utilization efficiency, hydrogel carriers-particularly those incorporating hyaluronic acid-enhance skin hydration, slow aging, and accelerate wound healing, indicating promising therapeutic potential.
AIMS: To review current treatment strategies and provide an updated perspective on the treatment of photoaging.
METHODS: We searched the PubMed and Web of Science library databases for eligible studies published within the past 5 years, categorizing and evaluating the effects of hydrogels with different carriers and active ingredients.
RESULTS: A total of 21 relevant studies were included, involving Lipid-based Hydrogels, Hyaluronic Acid-based Hydrogels, Chitosan-based Hydrogels, Polyacrylonitrile-modified κ-Carrageenan-based Hydrogels, Gellan Gum/Sodium Alginate-based Hydrogels, Recombinant Collagen-based Hydrogels, and Other Polymer-based Hydrogels.
CONCLUSIONS: The collected studies consistently demonstrate that hydrogel therapy is more effective than traditional treatments in reducing UV-induced skin damage and promoting skin repair and regeneration. In addition to improving drug utilization efficiency, hydrogel carriers-particularly those incorporating hyaluronic acid-enhance skin hydration, slow aging, and accelerate wound healing, indicating promising therapeutic potential.