Journal of the American Academy of Dermatology · 2005
Associations between ultraviolet radiation, basal cell carcinoma site and histology, host characteristics, and rate of development of further tumors.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Lovatt Tracy J, Lear John T, Bastrilles Jean, Wong Christina, Griffiths Christopher E M, Samarasinghe Venura, Roebuck Jamie, Ramachandran Sudarshan, Smith Andrew G, Jones Peter W, Fryer Anthony A, Strange Richard C
Аннотация
BACKGROUND: Patients with basal cell carcinoma (BCC) frequently develop further tumors during follow-up.
OBJECTIVE: We sought to elucidate the relative effects of pattern of ultraviolet radiation exposure, and site and histologic type of the first tumor, on the rate of increase in BCC numbers.
METHODS: We used negative binomial regression analysis to study the association of selected variables on the rate of increase in BCC numbers in 266 Caucasian patients who first presented with a tumor on the head/neck or trunk with nodular or superficial histology.
RESULTS: Patients with an initial truncal BCC with superficial histology demonstrated significantly faster increases in BCC numbers than did patients with other site and histology combinations.
CONCLUSIONS: These data indicate that site and histology define subsets of patients with BCC.
OBJECTIVE: We sought to elucidate the relative effects of pattern of ultraviolet radiation exposure, and site and histologic type of the first tumor, on the rate of increase in BCC numbers.
METHODS: We used negative binomial regression analysis to study the association of selected variables on the rate of increase in BCC numbers in 266 Caucasian patients who first presented with a tumor on the head/neck or trunk with nodular or superficial histology.
RESULTS: Patients with an initial truncal BCC with superficial histology demonstrated significantly faster increases in BCC numbers than did patients with other site and histology combinations.
CONCLUSIONS: These data indicate that site and histology define subsets of patients with BCC.